Abstract
Summary
Unilamellar vesicles of soy phosphatidylcholine and [14C]cholesterol were incubated with rat erythrocytes for up to 33 hr. From the kinetics of cholesterol equilibration between vesicles and erythrocytes we have calculated that erythrocyte cholesterol is present in two pools that equilibrate with a half-time of 2.3 ± 0.6 hr. The evidence suggests that the two pools, which are of comparable size, reflect the cholesterol present in the inner and outer portions of the lipid bilayer.
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