Abstract
Summary
The effect of alterations in urine flow rate and osmolality in urate excretion in the rat was examined by clearance techniques. The results of these studies indicate that large variations in water reab-sorption in the terminal segments of the nephron do not affect the rate of urate excretion. Vasopressin administration, while decreasing urinary flow rate and increasing the osmolality of the urine, was also without effect on urate excretion.
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