Abstract
Summary
The nature and appearance of RNA species in rat brain and liver cytoplasm have been examined by polyacryl-amide gel electrophoresis during the actively growing period. Accumulation of newly synthesized 28 and 18S rRNA is more rapid in immature than in mature liver cytoplasm. Two species of RNA heavier than 28S exist in cytoplasm of immature cerebrum, cerebellum, and liver and disappear from these tissues as they mature. Values of S based upon electrophoretic mobilities are 40 and 34S for these heavy RNAs.
Their exact nature and function during development are not known.
This work was supported in part by National Institutes of Health Research Grant HD 06682 and National Foundation Grant 1-285.
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