Abstract
Summary
Male thyroidectomized rats with varying levels of daily L-thyroxine injection were subjected to different amounts of physical activity to determine the influence of both factors on serum TG concentration. The study indicated that exercise is effective in lowering serum TG and that this hypotriglyceridemic response is directly related to the increasing severity of exercise. The control animals with intact thyroids had higher TG levels as compared to the thyroidectomized rats with differing replacement levels of L-T4 irrespective of the degree of physical activity. The differing feed intake in the various groups could not account for this hypotriglyceridemic effect. The lower body weight of the thyroidectomized animals, as compared to the control rats with intact thyroid glands, may be related, in part, to the lower TG concentration. The study suggests that the thyroid gland, in some manner, plays an important role in the hypotriglyceridemic effect of exercise.
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