Abstract
Summary
Platelet size, platelet count, and thrombopoietin levels in plasma fractions were determined in cyclic hemato-poietic (CH) dogs. Results show that platelet sizes varied inversely with platelet counts of CH dogs; significantly elevated levels of thrombopoietin were found in fractions of plasma from CH dogs at the beginning of active thrombopoiesis. These dogs serve as a useful model for studying cycling thrombopoiesis in man.
The authors thank Janet Jolly, Marilyn Cottrell, and Bill Wolfenbarger for technical assistance, Patricia Wayne for art and stenographic aid, and Dr. T. T. Odell, Jr., for helpful suggestions.
Get full access to this article
View all access options for this article.