Abstract
Summary
Carbonic anhydrase I (CA I) levels in mouse erythrocytes are influenced by thyroid status, while carbonic anhydrase II (CA II) levels appear to be unaffected. Adding propylthiouracil to the diets of normal mice (C57BL/6J) resulted in elevated erythrocyte CA I levels, while thyroid powder produced decreased levels. Panhypopi-tuitary mutants (DW/J dw/dw) have increased levels of erythrocyte CA I in comparison to their normal litter mates (DW/J + /?). These increased levels were decreased by adding thyroid powder to their diets.
We are indebted to Drs. Elizabeth Russell and Samuel Boyer for providing research facilities and comments on the manuscript, to Drs. Wes Beamer and Gary Chase for advice, and to Ms. Sharon K. Stroup for research assistance.
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