Abstract
Summary
The influence of chronic ethanol intake on carbohydrate metabolism was studied in mice. The results showed that daily ingestion of 10% or 30% ethanol for 30 or 60 days induced glucose intolerance, decreased and delayed glucose-mediated insulin response, as well as decreased peripheral insulin sensitivity. However, these metabolic derangements were not permanent as withdrawal of ethanol improved or restored these parameters to normal.
The authors wish to thank Mrs. Ruth M. Bonovich for preparation of this manuscript.
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