Abstract
Summary
Melatonin (12-100 μg/day) administered via subcutaneous Silastic implants prevented or suppressed light-induced testicular recrudescence in adult golden hamsters. In addition, melatonin (150 μg/day) induced marked testicular regression in sexually mature hamsters maintained on photostimulatory long days. These results clearly establish that exogenous melatonin can inhibit gonadal function in adult male hamsters.
The authors express their appreciation to Donald W. Carroll for expert assistance provided throughout this study.
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