Abstract
Summary
Agammaglobulinemic chickens died with fulminating parasitemias following infection with P. gallinaceum. When rescued from otherwise fatal infection by means of chloroquine therapy, B-cell deficient chickens resisted challenge infection with the same parasite. The data suggest that nonsterilizing immunity to malaria in chickens is B-cell independent.
We wish to thank Drs. Burton J. Landau and E. J. L. Soulsby for their helpful criticism in the preparation of this manuscript. This work was aided in part by US-PHA Grant AI No. 12710-01.
Get full access to this article
View all access options for this article.