The Response of Blood Flow to Altered Perfusion Pressure in Canine Adipose Tissue 1

Abstract

Summary

It is concluded that subcutaneous adipose tissue autoregulates its blood flow only weakly or not at all in the range of perfusion pressures employed in our studies. Instead, these experiments demonstrate that when perfusion pressure is altered in the fat pad, vascular resistance must change in an opposite direction since there is little tendency for the flow to return to control values. Therefore, the vascular bed is responding passively. Furthermore, there was little evidence of autoregulation in denervated tissues indicating that the extrinsic neural control does not mask an underlying ability to modulate flow.