Abstract
Summary
The induction of hepatitis in adult hamsters by H-l virus was documented by demonstrating an increase in serum SGOT and SGPT at 3-9 wk postinoculation. The electrophoresis pattern of LDH iso-enzymes showed a marked increase in the liver fraction (fraction 5) indicating liver damage in infected hamsters. The pathology displayed in diseased livers revealed a focal degeneration of hepatic cells although infiltration of white cells was not observed. H-l virus is apparently capable of producing hepatitis (without symptoms) in adult hamsters as well as cause hepatitis and severe cerebral disease in newborn hamsters.
Get full access to this article
View all access options for this article.