Abstract
Summary
Ferrocyanide was perfused through the vascular system of the isolated legs of 10 dogs. Ferric ion was then injected intramuscularly (not intravascularly) into the leg. The injected materials spread along the trabeculae of the tissues, rupturing the sheets of connective tissues which bind adjacent capsules together.
Precipitation of ferri-ferrocyanide on specific barriers in the extracapsular clefts in positions showed that sheets of fibrous connective tissue (frenulae) impeded the movement of materials in the trabeculae. The barriers consist of sheets of connective tissue which insert on adjacent fibrous capsules. The capsules enclose each cluster of muscle, glandular or other cells. These barriers appear to function in conjunction with the lymphatic drainage system.
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