Abstract
Summary
Anterior pituitaries of male rats were incubated for 4 hr in vitro and the amount of prolactin released when the medium was changed every 30 min was compared to the amount released when the prolactin was permitted to accumulate in the incubating medium. There were no consistent differences. Addition of various doses of ovine prolactin did not affect the release of rat prolactin in vitro. These results suggest that the anterior pituitary is not the site at which prolactin feeds back to inhibit its own secretion.
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