Abstract
Summary
Phenotypically normal mice expelled the intestinal nematode Nippostrongylus brasiliensis by Day 10-12 post-larval-inoculation. Congenitally athymic (nude) mice maintained, for their lifetime, infections of this parasite. The worm expulsion mechanism was generated by nude mice which had been given thymus gland implants 30 days prior to larval inoculations. The nude mouse may prove most useful in studies on mechanisms of immunity to helminthic infections.
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