Abstract
Summary
The enzyme system catalyzing the synthesis of taurine from sulfate and serine was assayed from a number of tissues of mammalian genera. This enzyme was present in the liver and heart of the cat, chick, dog, guinea pig, hamster, monkey, mouse, rabbit, rat, and sheep. The activity was higher in sheep liver, brain, heart, intestine, and kidney than in those tissues of rats. These data indicate that this mechanism for taurine biosynthesis is a constitutive animal enzyme which may be of significance when the transsulfuration pathway of taurine synthesis is impaired, or absent.
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