Abstract
Summary
Degrees of inactivation of HSV-1 and HSV-2 by four compounds were compared. The sensitivity of HSV-2 to p-chloromercuribenzoate and to chlorhexidine gluconate was found to be higher than that of HSV-1. Chlorhexidine gluconate could differentiate the HSV types more clearly than PCMB. This was ascertained with 15 HSV-1 and 18 HSV-2 strains. The inactivation occurred at 37° but not at 0°. On the other hand, iodoacetamide did not inactivate either type even at a concentration of 400 μg/ml. Photodynamic inactivation by acrinol was similar for both types.
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