Abstract
Summary
Liver and heart tissues from cold-acclimated rats were analyzed for content and subcellular distribution of the ions calcium, magnesium, potassium and sodium. The data provided indirect evidence of uncoupling of liver mitochondria in the cold-acclimated state, while casting doubt upon the hypothesis that massive calcium accumulation is the primary factor in the main-tainance of non-shivering thermogenesis. The observed ionic changes in the heart suggest a protective mechanism, involving magnesium, against cold-induced cardiopathy.
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