Abstract
Summary
The norepinephrine (NE) and epinephrine (E) contents of bovine middle cerebral (MCA) and lingual (LA) arteries were determined fluorometrically. Although the amount of E was almost identical in the 2 vessels, the MCA contained almost four times as much NE as the LA. Cumulative NE dose-response curves revealed a much greater reactivity of the LA than the MCA. An inverse relationship is demonstrated between NE content and vascular reactivity to this agent, and a similar relationship is suggested between NE content and the degree of functional innervation in some vascular beds.
The technical assistance of Mrs. Olha Holo-wecky is gratefully acknowledged.
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