Abstract
Summary
In vitro response to erythro-poietin of the bone marrow cells from patients with AML and ALL was studied. In the cases of AML the response was apparently suppressed, whereas in cases of ALL the response was well preserved although there was a marked reduction in numbers of erythroblast in the bone marrow of these patients before culture.
These results suggest that there may be a difference between the two types of leukemia with respect to the mode of involvement of the erythron.
This work was partially supported by the Research Grant from the Japanese Government. The authors are indebted for the kind cooperation of Dr. Shinobu Sakamoto in Tokyo Women's Medical College and Dr. Kogi Satomi in Kudan-zaka Hospital.
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