Abstract
Summary
This study presents evidence that the predominant enzyme present in cultivated human fibroblasts is aldolase A. The FDP/F1P activity ratio, K m and pH optima of the aldolase in crude fibroblast extracts are comparable to those previously described for aldolase A. No differences in activity or catalytic properties could be detected between the aldolase present in normal human fibroblasts and in fibroblasts from a patient with hereditary fructose intolerance.
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