Abstract
Summary
The antihemostatic and anticoagulant activities of heparin and heparitin sulfate fractions were compared. Heparitin sulfate D has the same antihemostatic activity as heparin but negligible anticoagulant activity, demonstrating differences in the molecular mechanisms of these two biological processes. The effects of heparitin sulfate fractions and modified heparins on hemostasis and coagulation are also compared in order to determine the minimum structural and chemical requirements for activity in these two phenomena.
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