Abstract
Summary
Whole-tissue binding of triiodothyronine was augmented in liver, kidney and skeletal muscle following adaptation of the rat to cold. The basis of the increased kidney binding of this hormone was increased binding to microsomes, the putative subcellular locus of hormonal deiodination. Cold induction of deiodinative sites in tissues is the suggested etiology of the increased deiodination of triiodothyronine in vivo after cold acclimation observed in previous studies.
Get full access to this article
View all access options for this article.