Abstract
Summary
Rats limited to food intake of 1 hr a day and allowed to run in an activity wheel developed gastric lesions which, on histologic examination, resembled human stress ulcers. The lesions in the animals started as small mucosal hemorrhages and developed progressively to form ulcers in the gastric mucosa. Some of the lesions penetrated to the submucosal layers. No thrombi were observed in the mucosal vessels.
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