Abstract
Summary
Reactivity of cytochrome oxidase, choline esterase, lactic, succinic, malic, and glucose-6-phosphate dehydrogenases, acid and alkaline phosphatases, and concentration of choline lipids were examined histochemically in cephalic sections of fetuses from manganese-deficient and pallid mice and their controls at 17 days of gestation. In the inner ear, enzymes and choline lipids were localized in the neural epithelium, but enzyme activity did not differ among the various groups. However, in epidermis of manganese-deficient fetuses there was reduced activity of cytochrome oxidase, choline esterase, and the false-positive yellow reaction for alkaline phosphatase, and reduced concentration of choline lipids.
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