Abstract
Summary
Three genetic groups of mice (DyDy, Dydy, and dydy) were studied at intervals of 6–14 wk. TCA intermediates were extracted, separated, and measured. Data indicate that mice with genetically induced muscular dystrophy (Strain 129) show alteration in several body tissues as well as in muscle itself. Of particular interest were changes measured in the brain of dystrophic mice. Support, but not proof, is given to the neurogenic concept of mouse muscular dystrophy.
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