Abstract
Summary
In the rabbit, under conditions in which mitoses accumulated in the acidophilic erythroblasts, none were observed in the basophilic erythroblasts. On the basis of certain assumptions, the basophilic erythroblasts were divided into two size classes: of average long diameters (as measured here) 10.3 and 8.4 nm. The larger have two pathways of development. One is to lose their cytoplasmic basophilia to form acidophils of the same size (Line 2 cells); the other is to divide amitotically into small basophils which eventually lose their cytoplasmic basophilia to become acidophils of the same size. Both groups of acidophils undergo mitotic division. Those from the large basophils divide once more; for those from the small basophils, it is a terminal division.
This investigation was supported by NIH HL-12236-05 and a Grant NGR-05-003-460 from NASA to the University of California, Berkeley.
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