Abstract
Summary
The percentage of human lymphocytes undergoing blastoid transformation induced by PHA was significantly increased by the presence of thymidine at concentrations between 0.02 mM and 0.2 mM. Concentrations under 0.002 mM were ineffective, whereas concentrations between 2 and 20 mM inhibited the blastogenic effect of PHA. Maximal inhibition was obtained with 8 mM of the nucleoside.
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