Abstract
Summary
The collagen hydroxyproline (hypro) from burned skin, unburned intact skin, and carcass of thermally burned rats has been studied. The statistically significant decrease in burned skin hypro 8 and 16 days after burn suggests that the major source of urinary peptide hypro early after burns is from degradation of thermally denatured skin collagen. The finding of a new layer of hypro-rich connective tissue under the burn site on Day 16 suggests that later elevations of urinary hypro may result from breakdown products of newly synthesized collagen as well as degradation of collagen at the burn site.
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