Abstract
Summary
Immunization of various inbred lines of young mice led to the appearance of monodisperse bands of gammaglobulin having antibody activity in the serum. Whereas the antibody titers achieved did not differ significantly, the proportion which developed these bands was as high as 60% in DBA/2 or C57BL/6 and F1 hybrids having these as one parent. This activity did not occur in A/J or CBA strains. These studies suggest an additional way in which genetic control might be exerted over the quantity of the immune response.
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