Abstract
Summary
A polyoma-induced cell line which spontaneously lost its tumor-causing capability while being passaged in vitro was described. This cell line retained both its appropriate H-2 alloantigen and its viral-related tumor antigen of transplantation type. The fortuitious observation of in vitro cross-reactivity between this cell line and a syngeneic 3-methylcholanthrene-induced tumor is discussed.
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