Abstract
Summary
The effect of oral calcium carbonate on serum levels and urinary excretion of calcium sodium and magnesium was evaluated in 10 patients with advanced renal disease. A rise in serum calcium which was observed in all patients was associated with increased urinary excretions of calcium, sodium and magnesium, suggesting that common reabsorptive mechanism(s) are underlying the renal handling of these ions also in advanced renal disease. A decrease in serum magnesium which was noticed in all patients could be explained by a decreased intestinal absorption, an increased urinary loss, or both.
This study was partly supported by a Grant FR-51 from the General Clinical Research Centers Program of the Division of Research Resources, National Institutes of Health.
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