Abstract
Summary
Rabbits were hyperimmunized with late rat and mouse pregnancy serum. After thorough absorption of the antisera with nonpregnancy plasma of the same strains of animal, up to 4 pregnancy-associated serum antigens were revealed in both rat and mouse pregnancy sera by immunodiffusion methods. They were mostly species-specific, no cross-reactions being seen with human pregnancy-associated plasma proteins. Only a partial cross-reaction was found between one of the rat and mouse pregnancy antigens. The rat pregnancy-associated serum antigens were not detected 10 days after parturition, nor were they found in the serum of newborn rats.
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