Abstract
Summary
The biological activity of interferon was determined after exposure to human secretions and excretions in vitro. Crude interferon lost some activity when incubated for 4 hr with control medium, but was usually inactivated by at least 50% more when incubated in the presence of serum, saliva, or cerebrospinal fluid, and by close to 100% when incubated with stool extract or bile. Interferon incubated for 24 hr with either serum or cerebrospinal fluid lost almost all activity.
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