Abstract
Summary
Adult cycling rats hypophysectomized on the morning of metestrus (day 1) were pituitary-autotransplanted or treated with 2.0 IU of prolactin twice daily by subcutaneous injection for 15 days. These two types of animals received either LH antiserum (LH A/S) or normal rabbit serum (NRS) on days 5 and 6 after hypophysectomy. Multiple blood samples were drawn by heart puncture from individual animals throughout the study, and the sera were analyzed for progesterone by radioimmunoassay. The results show that LH A/S was not effective in reducing serum progesterone levels maintained by exogenous or endogenous prolactin.
The authors express their appreciation to Miss Johanna McCann for her skilled assistance.
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