Abstract
Summary
The SZ-14 reorienting density gradient rotor (Ivan Sorvall, Inc., Newton, CT) having a sample capacity of approximately 50 ml may be used for the purification of viruses under appropriate conditions which are described. The procedure has been successfully applied to the purification of the diverse particle types associated with hepatitis B antigen under conditions minimizing the danger of laboratory contamination during centrifugation.
This study was supported by Contract 70-2236 from the National Heart and Lung Institute. A. M. P. is a Career Scientist of the Health Research Council of the City of New York under Contract I-533.
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