Abstract
Summary
Pellets of most steroids impeded hair regrowth in shaved areas. Estradiol-17β caused fatal obstruction of the urinary tract in males.
The diameters of the internal spermatic, ovarian, uterine, and femoral veins and the inferior vena cava in the mouse were measured in intact males, in orchidectomized males bearing glass pellets (controls) and steroid pellets, and in ovariectomized and ovariectomized-hysterectomized females with similar pellets. Mice with steroid pellets had significant increases, and sometimes significant decreases, in vein size compared to control mice with glass pellets. Venous response was greater after removal of both ovaries and uterus than after removal of ovaries only. The diameter of the internal spermatic vein appeared to depend on the influence of a steroid rather than on the presence of the testis as such.
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