Abstract
Summary
The recent finding that cyanate reacts specifically with the amino-terminal valine of the hemoglobin molecule in an irreversible carbamylation reaction has led us to develop a 14C-cyanate method for determining erythrocyte survival. The procedure is advantageous in that erythrocytes can be labeled either in vitro or in vivo.
The authors thank Mr. Neftali Rivera, Miss Barbara Bralver and Mr. James Leong for their excellent technical assistance.
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