Growth of the P388 Leukemia as an Ascites Tumor in Zinc-Deficient Mice

Abstract

Summary

The growth of P388 leukemia cells as an ascites tumor is markedly depressed in mice fed a zinc-deficient diet. Tritiated-thymidine labeling data suggest that zinc-deficient tumor cells accumulate in G₁.

We acknowledge with thanks the expert technical assistance of Mr. J. Meneses. DHB was supported by U.S. Public Health Service Medical Student Summer Research Fellowship No. FR 05355-10. Work performed under the auspices of the U.S. Atomic Energy Commission.