Abstract
Summary
Starvation results in a rapid and significant decrease in gulonolactone hydrolase activity in both males and females while gulonate NADP oxidoreductase activity is not diminished in either sex. The fall in gulonolactone hydrolase activity is followed by a significant fall in hepatic ascorbate content. Differences in both gulonolactone hydrolase and hepatic ascorbate, dependent on sex, are obliterated after 9 days of fasting.
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