Abstract
Summary
Four of five adult DBA/2J mice subjected to severe protein-calorie malnutrition in early life showed a notable reduction of blood glutamine levels while adult mice who had suffered a less severe nutritional deprivation showed a marked diminution of urinary taurine. It is suggested that there is a persistent metabolic adjustment in response to the need for increased nitrogen retention.
I thank Drs. Clark T. Randt and Douglas Gilmour for their valuable advice and constructive criticism. Also acknowledged are Mr. Gaston Veliz, Miss Virginia Hoagland and Miss Carroll Fisher for their technical assistance. This study was supported by the Grant Foundation and the American Institute for Mental Studies.
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