Abstract
Summary
Twelve hours after the intramuscular administration of a single 10 mg dose of human growth hormone (HGH), fasting blood samples were obtained and analyzed for levels of triglycerides and cholesterol. Growth hormone was found to raise fasting plasma triglycerides significantly in a group of 6 middle-aged and elderly diabetic subjects but not in 10 nondiabetic midde-aged and elderly controls. Smaller and less consistent increases were also observed in a group of 6 normal young men and in 6 young women who were taking contraceptive pills at the time. In no group was there any significant change in plasma cholesterol level 12 hr following growth hormone administration.
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