Effects of Prostaglandin B 2 on Renal Hemodynamics and Excretion 1

Abstract

Summary and Conclusion

The infusion of PGB₂ into canine renal arteries produces a dose related increase in total RBF and U _Na V. The increasing variability in RBF and N _Na V with increasing dose may be due to a transition from vasodilator to vasoconstrictor action. The results obtained demonstrate that PGB₂ affects renal hemodynamics and excretion qualitatively the same as PGE₁, PGE₂, PGA₁ and PGA₂.