Abstract
Summary
To determine whether adenovirus type 11 strains recovered from urine of children with acute hemorrhagic cystitis differed antigenically from the prototype strain, these strains were examined by cross HI tests. Four adenovirus type 11 strains (Dean, Scott, Heard, and Briggs) isolated from urine and the prototype Slobitski strain were tested. Reaction times of virus with antibody varied between 4 min and 21 hr. At the shortest reaction time, strain differences were most pronounced. The Scott and Briggs urine strains showed less resemblance to the Slobitski strain and other urine strains. At longer reaction times, titer differences disappeared. Except for these differences, which were not marked, the adenovirus type 11 strains from urine appeared antigenically similar to the prototype strain.
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