Abstract
Summary
Somatic antigen prepared from either nontypable nonencapulated or type b encapsulated H. influenzae strains is effective in low concentration in causing transformation in vitro of nonfiber-adherent human lymphocytes. Capsular H. influenzae polyribose phosphate is an ineffective stimulant for human lymphocyte transformation in vitro. Significant transformation of peripheral blood lymphocytes from all normal adults tested was effected by the somatic antigen.
The author thanks Bruce B. Cartwright and Sara E. Hieny for their excellent technical assistance.
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