Abstract
Summary
Male rats, fed ad libitum, were exposed to 30% and 47% oxygen environments (balance, N2) at 1 atm for periods of time varying from 1 to 4 days. The rats exposed to increased oxygen tensions for 3 or 4 days gained more weight than controls. Fatty acid contents of liver and adipose tissue of the experimental group at 4 days of exposure were higher than the fatty acid contents found in these tissues for the control group. Conversion of acetate to fatty acids was found to be significantly higher in liver and adipose tissue of oxygen enriched animals. The conclusion is drawn that these findings are the result solely of an increase in alveolar oxygen tension.
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