Abstract
Summary
After 3H-estradiol injection, radioactivity was found to concentrate in certain cells in the rat spinal cord. The topography was determined by dry-mount autoradiography. The greatest density at all levels occurred in laminae I and II of the dorsal horn. In the lumbar cord, a second group of labeled cells appeared in the dorsal portion of lamina X. Occasional scattered labeled cells appeared throughout the remaining gray and white matter. It is suggested that the radioactivity-concentrating cells are estradiol target sites involved in sex-related sensation and reflexes.
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