Abstract
Summary
Preference for solutions of various salts and for quinine sulfate and hydrochloric acid was compared in spontaneously hypertensive (SH) male rats and in two groups of normotensive control rats by a two-bottle preference test. SH rats exhibited a significantly increased preference for salt solutions containing Na+ and K+, but for neither quinine nor hydrochloric acid. When given a choice between 0.30 M NaCl and water, SH rats imbibed 2–5 times the amount of Na+ imbibed by the controls. SH rats imbibed significantly more total fluid (salt and water) than did controls as long as salts were presented. However, as soon as water alone was presented, total fluid intake returned to control levels.
The authors wish to thank Dr. Yukio Yamori, Kyoto University, Kyoto, Japan for his kind assistance in obtaining normotensive Wistar/Kyoto (WI/KY) rats.
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