Abstract
Summary
Newcastle and parainfluenza I viruses when incubated with mouse or chick embryo erythrocytes at low multiplicity sensitized the red cells to hemolysis by antiviral antibody and complement. Two strains of influenza virus showed little or no sensitizing activity to influenza antibody. As determined by hemolytic titer paramyxovirus bound to erythrocytes at 37° could not be removed by pretreatment with antibody alone and virus absorbed at 4° was only partially removed by antibody at this temperature. Effects of inactivating infectivity and viral neuraminidase on sensitizing ability of the viruses were examined.
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