Abstract
Summary
A phenomenon termed “xenogeneic resistance” to hemopoietic repopulation by rat bone marrow was found to exist in supralethally irradiated (1000-1100 R) C57BL/6 mice and their F1 hybrids, but not in mice of 5 other strains, studied by means of the spleen colony method. The similarities of this phenomenon to the phenomena known variously as “hybrid resistance,” “CFU repression,” or “poor growth phenomenon” suggest that these may all represent different manifestations of a single mechanism.
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