Abstract
Summary
A comparative survey of several properties of acid-soluble collagens extracted from normal skin and carrageenin granulomas in guinea pigs has failed to reveal any qualitative difference that might explain the peculiar susceptibility of granuloma-derived collagen to degradation and resorption. The only quantitative difference found was a higher concentration of a subunits and a lower concentration of β subunits in carrageenin granuloma collagen, compared with normal skin collagen. It is suggested that this difference might explain, at least in part, the ready degradation of collagen in the carrageenin granuloma.
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